Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211825 | 0.92 | ACE (0.34) | ACE | |
| SCHEMBL11213081 | 0.88 | ACE (0.32) | ACE | |
| SCHEMBL11213089 | 0.80 | ACE (0.43) | ACE | |
| SCHEMBL11210064 | 0.80 | ACE (0.34) | ACE | |
| SCHEMBL11214429 | 0.79 | ACE (0.38) | ACE | |
| SCHEMBL11257080 | 0.78 | ACE (0.37) | ACE | |
| SCHEMBL11210160 | 0.78 | ACE (0.37) | ACE | |
| SCHEMBL11219671 | 0.77 | LMNA (0.50) | ACE | |
| SCHEMBL11210570 | 0.77 | LMNA (0.50) | ACE | |
| SCHEMBL11214163 | 0.77 | ACE (0.52) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |