Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210160 | 0.93 | ACE (0.37) | ACE | |
| SCHEMBL11257080 | 0.93 | ACE (0.37) | ACE | |
| SCHEMBL11212426 | 0.87 | ACE (0.31) | ACE | |
| SCHEMBL11210375 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL11208609 | 0.80 | ACE (0.41) | ACE | |
| SCHEMBL11210192 | 0.79 | ACE (0.38) | ACE | |
| SCHEMBL11213000 | 0.78 | ACE (0.50) | ACEKMT2A | |
| SCHEMBL11214442 | 0.78 | ACE (0.43) | ACEKMT2AALDH1A1 | |
| SCHEMBL11211825 | 0.78 | ACE (0.34) | ACE | |
| SCHEMBL11213081 | 0.77 | ACE (0.32) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |