Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207157 | 0.83 | KMT2A (0.45) | ALDH1A1MAPTLMNA | |
| SCHEMBL11202315 | 0.81 | MAPT (0.45) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11268767 | 0.81 | MAPT (0.56) | ALDH1A1MAPTCYP4F2CYP4A11KDM4E | |
| SCHEMBL11206369 | 0.80 | SMN1; SMN2 (0.44) | ALDH1A1MAPTCYP4F2CYP4A11KDM4E | |
| SCHEMBL11205681 | 0.79 | MAPT (0.42) | ALDH1A1MAPTCYP4F2CYP4A11KDM4E | |
| SCHEMBL11207422 | 0.79 | KCNA3 (0.42) | ALDH1A1MAPTLMNA | |
| SCHEMBL11214189 | 0.79 | MEN1 (0.40) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11201202 | 0.78 | KCNA3 (0.41) | ALDH1A1MAPTLMNA | |
| SCHEMBL11203299 | 0.78 | KCNA3 (0.41) | ALDH1A1MAPTLMNA | |
| SCHEMBL11206024 | 0.78 | KCNA3 (0.41) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |