Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265171 | 0.82 | LMNA (0.54) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11208727 | 0.81 | ALDH1A1 (0.42) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11264433 | 0.80 | LMNA (0.68) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11267381 | 0.79 | MAPT (0.55) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11259163 | 0.78 | MAPT (0.57) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11269898 | 0.78 | LMNA (0.56) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11267425 | 0.78 | LMNA (0.56) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11268263 | 0.77 | LMNA (0.58) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11268538 | 0.77 | LMNA (0.58) | MAPTLMNAABCB11MAPK1ALDH1A1 | |
| SCHEMBL11266263 | 0.77 | LMNA (0.58) | MAPTLMNAABCB11MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |