Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207422 | 0.96 | KCNA3 (0.42) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL11203299 | 0.95 | KCNA3 (0.41) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL11208527 | 0.95 | KCNA3 (0.41) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL11206024 | 0.95 | KCNA3 (0.41) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL11201202 | 0.95 | KCNA3 (0.41) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL11204880 | 0.92 | OPRM1 (0.43) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL11022009 | 0.92 | LMNA (0.41) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL7431043 | 0.91 | ALDH1A1 (0.41) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL10878293 | 0.90 | SMN1; SMN2 (0.40) | KMT2AMEN1LMNAPOLBPKM | |
| SCHEMBL11205749 | 0.90 | CTDSP1 (0.38) | KMT2AMEN1LMNAPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |