SCHEMBL11208758

SCHEMBL11208758

O=C(O)c1ccc(Cc2ccccc2)c(Cc2ccccc2)c1O

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.57
PTPN2 P17706 1/20 0.57
PTPN6 P29350 1/20 0.57
POLB P06746 1/20 0.49
GPR35 Q9HC97 1/20 0.49
TSHR P16473 1/20 0.47
HNF4A P41235 1/20 0.47
ME2 P23368 1/20 0.44
ME1 P48163 1/20 0.44
ME3 Q16798 1/20 0.44
BCL2 P10415 1/20 0.44
BCL2L1 Q07817 1/20 0.44
HMGB1 P09429 1/20 0.44
CXCL12 P48061 1/20 0.44
LDHA P00338 1/20 0.43
ALOX5 P09917 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28180065 0.87 PTPN1 (0.46) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL2227624 0.86 PTPN1 (0.51) PTPN1PTPN2PTPN6TSHRHNF4A
SCHEMBL10721869 0.84 HNF4A (0.57) PTPN1PTPN2PTPN6POLBGPR35
SCHEMBL1888529 0.83 PTPN1 (0.49) PTPN1PTPN2PTPN6TSHRHNF4A
SCHEMBL27738449 0.81 PTPN1 (0.55) PTPN1PTPN2PTPN6TSHRHNF4A
SCHEMBL4616605 0.81 PTPN1 (0.55) PTPN1PTPN2PTPN6TSHRHNF4A
SCHEMBL17941538 0.81 ALDH1A1 (0.49) PTPN1PTPN2PTPN6POLBGPR35
SCHEMBL28188913 0.81 PTPN1 (0.47) PTPN1PTPN2PTPN6POLBTSHR
SCHEMBL28441961 0.81 PPARA (0.50) BCL2L1
SCHEMBL28428838 0.80 PTPN1 (0.46) PTPN1PTPN2PTPN6TSHRHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4418942-A WRINKLE RESISTANCE; HYDROPHOBIC SURFACTANTS; LOW GAS PERMEABILITY FUJI PHOTO FILM CO., LTD. (JP) 1983-12-06 US disclosed