SCHEMBL5387344

SCHEMBL5387344

CCC(C)(O[SiH3])c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.43
ALDH1A1 P00352 3/20 0.40
TAAR1 Q96RJ0 2/20 0.40
ALOX15 P16050 1/20 0.40
KCNN4 O15554 2/20 0.39
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
SLC6A2 P23975 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 1/20 0.34
NR3C2 P08235 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
TACR1 P25103 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3481487 0.83 MAPK1 (0.40) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL11208770 0.82 MAPK1 (0.52) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL7448596 0.82 MAPK1 (0.46) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL9686002 0.81 MAPK1 (0.41) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL3481672 0.80 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL5180283 0.80 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL1774346 0.80 MAPK1 (0.44) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL15302558 0.79 TAAR1 (0.52) MAPK1ALDH1A1TAAR1ALOX15CYP2C19
SCHEMBL297402 0.78 ALDH1A1 (0.56) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL28331955 0.77 MAPK1 (0.41) MAPK1ALDH1A1TAAR1ALOX15KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN disclosed
CN-114085382-A Hydrogen-containing poly titanium boron siloxane flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2022-02-25 CN disclosed
CN-110382625-B Curable organopolysiloxane composition and semiconductor device 杜邦东丽特殊材料株式会社 2022-02-18 CN disclosed
CN-110691825-A Release agent composition for silicone adhesive and release film 陶氏东丽株式会社 2020-01-14 CN disclosed
CN-110382625-A CURABLE ORGANOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE 道康宁东丽株式会社 2019-10-25 CN disclosed
US-7205085-B2 Composition having permitivity being radiation-sensitively changeable and method for forming permitivity pattern JSR CORPORATION (JP) 2007-04-17 US disclosed
US-7125647-B2 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2006-10-24 US disclosed
EP-1413924-A1 COMPOSITION HAVING PERMITIVITY BEING RADIATION-SENSITIVELY CHANGEABLE AND METHOD FOR FORMING PERMITIVITY PATTERN JSR Corporation (JP) 2004-04-28 EP disclosed
US-20040005506-A1 Composition having permitivity being radiation-sensitively changeable and method for forming permitivity pattern JSR CORPORATION (JP) 2004-01-08 US disclosed
EP-1375597-A1 RADIATION-SENSITIVE COMPOSITION CHANGING IN REFRACTIVE INDEX AND UTILIZATION THEREOF JSR Corporation (JP) 2004-01-02 EP disclosed
US-20030171468-A1 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2003-09-11 US disclosed
US-4831091-A USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES CHISSO CORPORATION (JP) 1989-05-16 US disclosed