Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.44 |
| ▸ | SGPL1 | O95470 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209631 | 0.96 | S1PR1 (0.44) | S1PR1SGPL1MAPTSMN1; SMN2THRB | |
| SCHEMBL11207311 | 0.90 | S1PR1 (0.45) | S1PR1SGPL1MAPT | |
| SCHEMBL8763562 | 0.89 | TP53 (0.47) | S1PR1SGPL1 | |
| SCHEMBL11208842 | 0.87 | S1PR1 (0.43) | S1PR1SGPL1MAPTSMN1; SMN2 | |
| SCHEMBL11210804 | 0.86 | S1PR1 (0.44) | S1PR1SGPL1SMN1; SMN2 | |
| SCHEMBL8764265 | 0.85 | MCHR1 (0.43) | S1PR1SGPL1MAPT | |
| SCHEMBL11212529 | 0.84 | S1PR3 (0.48) | S1PR1MAPTSMN1; SMN2THRBDRD2 | |
| SCHEMBL11213297 | 0.84 | S1PR3 (0.53) | S1PR1SGPL1MAPTSMN1; SMN2THRB | |
| SCHEMBL11214904 | 0.83 | S1PR3 (0.55) | S1PR1SGPL1MAPTSMN1; SMN2THRB | |
| SCHEMBL11209822 | 0.82 | CYP3A4 (0.53) | S1PR1SGPL1MAPTSMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |