Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207311 | 0.91 | S1PR1 (0.45) | S1PR1SGPL1 | |
| SCHEMBL8763749 | 0.91 | S1PR1 (0.52) | TP53TSHRPLA2G4BS1PR1SGPL1 | |
| SCHEMBL11209631 | 0.89 | S1PR1 (0.44) | S1PR1SGPL1 | |
| SCHEMBL11208804 | 0.89 | S1PR1 (0.44) | S1PR1SGPL1 | |
| SCHEMBL11210804 | 0.89 | S1PR1 (0.44) | S1PR1SGPL1 | |
| SCHEMBL11208842 | 0.87 | S1PR1 (0.43) | S1PR1SGPL1 | |
| SCHEMBL8764265 | 0.87 | MCHR1 (0.43) | TSHRS1PR1SGPL1 | |
| SCHEMBL8535829 | 0.82 | TP53 (0.55) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL14192553 | 0.81 | MCHR1 (0.44) | S1PR1SGPL1 | |
| SCHEMBL11208930 | 0.80 | MCHR1 (0.40) | TP53S1PR1SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566379-B1 | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL IND (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5346646-A | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0566379-A2 | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |