Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763562 | 0.87 | TP53 (0.47) | TSHRS1PR1SGPL1 | |
| SCHEMBL8533556 | 0.87 | TAOK3 (0.45) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11208804 | 0.85 | S1PR1 (0.44) | MAPTS1PR1SGPL1 | |
| SCHEMBL11209631 | 0.85 | S1PR1 (0.44) | MAPTS1PR1SGPL1 | |
| SCHEMBL11207311 | 0.84 | S1PR1 (0.45) | MCHR1MAPTCYP3A4S1PR1SGPL1 | |
| SCHEMBL11210804 | 0.82 | S1PR1 (0.44) | CYP3A4S1PR1SGPL1 | |
| SCHEMBL11208842 | 0.81 | S1PR1 (0.43) | MAPTCYP3A4S1PR1SGPL1 | |
| SCHEMBL8763749 | 0.80 | S1PR1 (0.52) | TSHRS1PR1SGPL1 | |
| SCHEMBL3553425 | 0.78 | LMNA (0.47) | MCHR1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL9663346 | 0.78 | NPC1 (0.62) | MAPTALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566379-B1 | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL IND (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5346646-A | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0566379-A2 | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |