Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568065 | 0.86 | MIF (0.49) | MAPTHPGDKMT2AOPRK1L3MBTL1 | |
| SCHEMBL11367151 | 0.86 | MAPT (0.47) | MAPTHPGDKMT2AOPRK1L3MBTL1 | |
| SCHEMBL11350394 | 0.82 | MAPT (0.50) | MAPTKMT2AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL11366588 | 0.81 | ALDH1A1 (0.51) | MAPTHPGDKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11357601 | 0.79 | MAPT (0.46) | MAPTHPGDKMT2AOPRK1L3MBTL1 | |
| SCHEMBL11363412 | 0.79 | MAPT (0.43) | MAPTHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4040996 | 0.78 | SMN1; SMN2 (0.46) | MAPTHPGDKMT2AL3MBTL1G6PD | |
| SCHEMBL31165708 | 0.78 | SMN1; SMN2 (0.46) | MAPTHPGDKMT2AL3MBTL1G6PD | |
| SCHEMBL8116321 | 0.78 | MAPT (0.43) | MAPTHPGDKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11475471 | 0.78 | MAPT (0.43) | MAPTHPGDKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039795-B1 | PROCESS FOR THE PREPARATION OF 1,2-BENZISOTHIAZOLES | BASF Aktiengesellschaft (DE) | 1983-10-12 | — | — | EP | disclosed |
| EP-0039795-A1 | Process for the preparation of 1,2-benzisothiazoles | BASF Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
| US-4277477-A | TREATING CARDIAC ARRHYTHMIA | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| EP-0000750-A1 | 1,2-Benzisothiazoles and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-02-21 | — | — | EP | disclosed |