Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208842 | 0.93 | S1PR1 (0.43) | MAPTS1PR1MGLLSGPL1LMNA | |
| SCHEMBL11210804 | 0.92 | S1PR1 (0.44) | S1PR1MGLLSGPL1LMNA | |
| SCHEMBL11214851 | 0.84 | MCHR1 (0.48) | MCHR1MAPTALDH1A1PPARDPPARA | |
| SCHEMBL11209164 | 0.83 | MCHR1 (0.49) | MCHR1MAPTALDH1A1PPARDPPARA | |
| SCHEMBL11209604 | 0.82 | MCHR1 (0.46) | MCHR1PPARDPPARAPRSS1ACR | |
| SCHEMBL11213220 | 0.82 | CYP11B1 (0.43) | MCHR1MAPTALDH1A1PPARDPPARA | |
| SCHEMBL11075730 | 0.81 | MCHR1 (0.46) | MCHR1PPARDPPARAS1PR1MGLL | |
| SCHEMBL11207311 | 0.81 | S1PR1 (0.45) | MCHR1MAPTS1PR1SGPL1LMNA | |
| SCHEMBL11209612 | 0.80 | CYP3A4 (0.46) | MCHR1S1PR1MGLLSGPL1LMNA | |
| SCHEMBL11211358 | 0.80 | CYP3A4 (0.46) | MCHR1S1PR1MGLLSGPL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |