Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214851 | 0.92 | MCHR1 (0.48) | MCHR1CYP19A1SRD5A1SRD5A2MAPT | |
| SCHEMBL11209604 | 0.90 | MCHR1 (0.46) | MCHR1CYP19A1SRD5A1SRD5A2PPARD | |
| SCHEMBL11075730 | 0.89 | MCHR1 (0.46) | MCHR1CYP19A1PPARDPPARAMGLL | |
| SCHEMBL11209532 | 0.88 | CYP3A4 (0.46) | MCHR1CYP19A1LMNAMGLL | |
| SCHEMBL11211358 | 0.88 | CYP3A4 (0.46) | MCHR1CYP19A1LMNAMGLL | |
| SCHEMBL11209612 | 0.88 | CYP3A4 (0.46) | MCHR1CYP19A1LMNAMGLL | |
| SCHEMBL11213220 | 0.85 | CYP11B1 (0.43) | MCHR1MAPTTP53ALDH1A1CYP11B1 | |
| SCHEMBL11208930 | 0.83 | MCHR1 (0.40) | MCHR1SRD5A1SRD5A2MAPTTP53 | |
| SCHEMBL11208842 | 0.81 | S1PR1 (0.43) | MAPTLMNAMGLL | |
| SCHEMBL11210804 | 0.80 | S1PR1 (0.44) | LMNAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |