Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129815 | 0.92 | — | — | |
| Water SCHEMBL27802509 | 0.88 | — | — | |
| SCHEMBL29580952 | 0.88 | CA12 (0.53) | CA12CA2CA9CA14CA3 | |
| Hydrochloric Acid SCHEMBL22771623 | 0.88 | — | — | |
| SCHEMBL29580954 | 0.88 | CA12 (0.53) | CA12CA2CA9CA14CA3 | |
| SCHEMBL5715864 | 0.88 | CA12 (0.53) | CA12CA2CA9CA14CA3 | |
| Ammonia Solution, Strong SCHEMBL9405419 | 0.88 | — | — | |
| SCHEMBL27554512 | 0.88 | — | — | |
| SCHEMBL23945948 | 0.81 | SIGMAR1 (0.46) | CA12CA2CA9CA14CA3 | |
| Dimethylamine SCHEMBL10626203 | 0.81 | CA12 (0.39) | CA12CA2CA9CA14CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044655-B1 | GAS SEPARATION PROCESSES USING LIQUID SORBENTS CONTAINING BIMETALLIC SALT COMPLEXES AND ALKYLATION INHIBITORS FOR USE THEREIN | Tenneco Resins, Inc. (US) | 1983-10-05 | — | — | EP | disclosed |
| US-4353840-A | REVERSIBLE ABSORPTION | TENNECO CHEMICALS, INC. (US) | 1982-10-12 | — | — | US | disclosed |
| US-4317950-A | SEPARATION OF ETHYLENE AND/OR PROPYLENE FROM GAS STREAMS USING AN ADSORBER OF A BIMETAL SALT COMPLEX | TENNECO CHEMICALS, INC. (US) | 1982-03-02 | — | — | US | disclosed |
| EP-0044655-A1 | Gas separation processes using liquid sorbents containing bimetallic salt complexes and alkylation inhibitors for use therein | Tenneco Resins, Inc. (US) | 1982-01-27 | — | — | EP | disclosed |