SCHEMBL11209028

SCHEMBL11209028

CCCCc1ccc(CCN(CCC#N)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
BCHE P06276 3/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
RORC P51449 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11209758 0.88 BCHE (0.48) KCNH2BCHE
SCHEMBL8055910 0.86 MEN1 (0.47) CA12CA1CA2ALDH1A1USP2
SCHEMBL11212081 0.85 CYP2C19 (0.44) CA12CA1CA2RORCALDH1A1
SCHEMBL9323694 0.85 HSD17B10 (0.44) DRD3ALDH1A1USP2HSD17B10MEN1
SCHEMBL30505454 0.83 KCNH2 (0.55) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL11208914 0.82 ALDH1A1 (0.41) SLC6A2SLC6A4SLC6A3CA12CA1
SCHEMBL28906259 0.82 NPC1 (0.43) KCNH2DRD3ALDH1A1USP2HSD17B10
SCHEMBL10491085 0.82 NPC1 (0.43) KCNH2DRD3ALDH1A1USP2HSD17B10
SCHEMBL10491081 0.82 NPC1 (0.43) KCNH2DRD3ALDH1A1USP2HSD17B10
SCHEMBL11800465 0.82 NPC1 (0.43) KCNH2DRD3ALDH1A1USP2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed