Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736366 | 0.94 | LTA4H (0.33) | LTA4HSIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL23736383 | 0.94 | LTA4H (0.33) | LTA4HSIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL23736374 | 0.91 | LTA4H (0.33) | LTA4HDRD2DRD4DRD3CYP2D6 | |
| SCHEMBL6567107 | 0.91 | LTA4H (0.39) | LTA4HCYP2D6SLC29A1CYP2C9HSD17B10 | |
| SCHEMBL79285 | 0.91 | LTA4H (0.39) | LTA4HCYP2D6SLC29A1CYP2C9HSD17B10 | |
| SCHEMBL3426360 | 0.89 | LTA4H (0.34) | LTA4HDRD2DRD4DRD3CYP2D6 | |
| SCHEMBL11787675 | 0.89 | LTA4H (0.38) | LTA4HCYP2D6SLC29A1CYP2C9HSD17B10 | |
| SCHEMBL9320360 | 0.89 | LTA4H (0.38) | LTA4HCYP2D6SLC29A1CYP2C9HSD17B10 | |
| SCHEMBL522366 | 0.89 | LTA4H (0.37) | LTA4HCYP2D6SLC29A1CYP2C9HSD17B10 | |
| SCHEMBL1548847 | 0.86 | CYP2D6 (0.35) | LTA4HDRD2DRD4DRD3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405705-A | HYDROPHILIC | TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
| US-4187112-A | Photosensitive plate containing nitrogen containing condensation type polyesters | TOYOBO CO., LTD. (JP) | 1980-02-05 | — | — | US | disclosed |