Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95865 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL13665394 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL535558 | 0.80 | ALDH1A1 (0.66) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL3391996 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL39472 | 0.79 | HPGD (0.78) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL8699631 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL7875585 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL11452427 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL26509809 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL28056476 | 0.77 | L3MBTL1 (0.81) | ALDH1A1TDP1RAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022387-B1 | PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES BY THE REACTION OF AN ACTIVATED HALOBENZENE WITH AN ORGANIC COMPOUND CONTAINING AN OXYGEN OR SULPHUR ANION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-01-05 | — | — | EP | disclosed |
| US-4287125-A | Preparation of benzenoid ethers and thioethers | RHONE-POULENC INDUSTRIES (FR) | 1981-09-01 | — | — | US | disclosed |
| EP-0022387-A1 | Process for the preparation of benzene derivatives by the reaction of an activated halobenzene with an organic compound containing an oxygen or sulphur anion | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-01-14 | — | — | EP | disclosed |