SCHEMBL11209189

SCHEMBL11209189

Cc1ccc(CN(C)C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
HSP90AA1 P07900 1/20 0.51
KMT2A Q03164 3/20 0.49
HPGD P15428 1/20 0.49
CTBP2 P56545 1/20 0.48
LIPE Q05469 1/20 0.48
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
MMP13 P45452 1/20 0.46
MEN1 O00255 1/20 0.46
CNR1 P21554 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL171719 0.85 ALDH1A1 (0.61) RAB9ANPC1CA12CA9HSP90AA1
SCHEMBL26087008 0.84 ALDH1A1 (0.56) RAB9ANPC1CA12CA9KMT2A
SCHEMBL19513365 0.83 HSP90AA1 (0.49) RAB9ANPC1CA12CA9HSP90AA1
SCHEMBL1935803 0.83 RAB9A (0.52) RAB9ANPC1CA12CA9KMT2A
SCHEMBL6412658 0.82 HSP90AA1 (0.43) RAB9ANPC1CA12CA9HSP90AA1
SCHEMBL6412652 0.82 HSP90AA1 (0.43) RAB9ANPC1CA12CA9HSP90AA1
SCHEMBL180384 0.82 NPC1 (0.73) RAB9ANPC1CA12CA9KMT2A
SCHEMBL23972262 0.81 RAB9A (0.66) RAB9ANPC1HSP90AA1KMT2AALDH1A1
SCHEMBL1893045 0.81 PYCR1 (0.52) RAB9ANPC1CA12CA9KMT2A
SCHEMBL3236512 0.81 RAB9A (0.50) RAB9ANPC1CA12CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0011712-B1 PREPARATION OF BENZALDEHYDE DIALKYL ACETALS SUBSTITUTED IN THE 4-POSITION BASF Aktiengesellschaft (DE) 1983-06-15 EP disclosed
US-4284825-A INTERMEDIATES FOR PERFUMES, CROP PROTECTION AGENTS BASF AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0011712-A2 Preparation of benzaldehyde dialkyl acetals substituted in the 4-position BASF Aktiengesellschaft (DE) 1980-06-11 EP disclosed