Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209267 | 1.00 | POLB (0.46) | POLBCYP2D6TRPA1MAPTMEN1 | |
| SCHEMBL8778749 | 0.84 | HSD17B10 (0.50) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL10452515 | 0.82 | KMT2A (0.40) | POLBKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL11220017 | 0.78 | POLB (0.58) | POLBCYP2D6TRPA1MAPTMEN1 | |
| SCHEMBL8997405 | 0.76 | ALDH1A1 (0.52) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11220009 | 0.74 | KMT2A (0.42) | POLBCYP2D6TRPA1MAPTMEN1 | |
| SCHEMBL14462168 | 0.73 | MAPT (0.48) | POLBCYP2D6TRPA1MAPTMEN1 | |
| SCHEMBL11221519 | 0.73 | POLB (0.44) | POLBCYP2D6TRPA1MAPTMEN1 | |
| SCHEMBL11220047 | 0.73 | KMT2A (0.47) | POLBCYP2D6TRPA1MAPTMEN1 | |
| SCHEMBL11209270 | 0.72 | POLB (0.47) | POLBCYP2D6TRPA1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337194-A | MULTISTEP, WITH PURIFICATION BY WASHING AFTER EACH COUPLING | C. M. INDUSTRIES (FR) | 1982-06-29 | — | — | US | claimed |
| EP-0017536-A2 | Process for the preparation of somatostatine | SANOFI S.A. (FR) | 1980-10-15 | — | — | EP | claimed |
| EP-0017536-B1 | PROCESS FOR THE PREPARATION OF SOMATOSTATINE | SANOFI S.A. (FR) | 1983-03-23 | — | — | EP | disclosed |
| US-4337194-A | MULTISTEP, WITH PURIFICATION BY WASHING AFTER EACH COUPLING | C. M. INDUSTRIES (FR) | 1982-06-29 | — | — | US | disclosed |
| EP-0017536-A2 | Process for the preparation of somatostatine | SANOFI S.A. (FR) | 1980-10-15 | — | — | EP | disclosed |