Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452515 | 0.88 | KMT2A (0.40) | ALDH1A1KMT2ATSHRHSD17B10POLB | |
| SCHEMBL8778749 | 0.82 | HSD17B10 (0.50) | ALDH1A1KMT2ATSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL1018465 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2ATSHRHSD17B10TAS2R14 | |
| SCHEMBL402122 | 0.79 | KMT2A (0.59) | ALDH1A1KMT2ATSHRHSD17B10TP53 | |
| SCHEMBL11581819 | 0.78 | TSHR (0.58) | ALDH1A1KMT2ATSHRHSD17B10TP53 | |
| SCHEMBL1018823 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2ATSHRHSD17B10TP53 | |
| SCHEMBL1060743 | 0.76 | TSHR (0.56) | ALDH1A1KMT2ATSHRHSD17B10TAS2R14 | |
| SCHEMBL11209267 | 0.76 | POLB (0.46) | ALDH1A1KMT2AHSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL11209277 | 0.76 | POLB (0.46) | ALDH1A1KMT2AHSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL27609587 | 0.76 | KMT2A (0.45) | ALDH1A1KMT2ATSHRHSD17B10TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500024-A | DISCOLORATION INHIBITION; INTRAOCULAR AND CONTACT LENSES; BONDED TO POLYMER | CIBA-GEIGY CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| US-5399692-A | Ultraviolet absorbing benzophenone sulfonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-5298033-A | An absorber bonded to lens formed of hydroxyethyl methacrylate | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |