Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15466517 | 0.74 | NOTUM (0.43) | NOTUMHTR2AHTR2C | |
| SCHEMBL11209343 | 0.70 | NOTUM (0.40) | NOTUMHTR2AHTR2C | |
| SCHEMBL1873666 | 0.69 | NOTUM (0.42) | NOTUMHTR2AHTR2C | |
| SCHEMBL29874430 | 0.66 | HTR2A (0.44) | NOTUMHTR2AHTR2C | |
| SCHEMBL10917532 | 0.66 | HTR2A (0.39) | NOTUMHTR2AHTR2C | |
| SCHEMBL3050639 | 0.66 | HTR2A (0.44) | NOTUMHTR2AHTR2C | |
| Hydroxyamine SCHEMBL9656514 | 0.66 | NOTUM (0.39) | NOTUMHTR2AHTR2C | |
| SCHEMBL10960778 | 0.63 | NOTUM (0.37) | NOTUMHTR2AHTR2C | |
| SCHEMBL3203383 | 0.63 | NOTUM (0.37) | NOTUMHTR2AHTR2C | |
| Benzoquinone SCHEMBL6697569 | 0.62 | NOTUM (0.42) | NOTUMHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4396773-A | 1,1'-[Dithiobis(2-alkyl-1-oxo-3,1-propanediyl)]-bis[2,3-dihydro-1H-indole-2-carboxylic acids and derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |