SCHEMBL8930618

SCHEMBL8930618

Oc1c(Cc2ccccc2)cc(Cc2cc(Cc3ccccc3)c(O)c(O)c2O)c(O)c1O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.61
BCL2L1 Q07817 1/20 0.61
PTPN1 P18031 3/20 0.55
PTPN2 P17706 1/20 0.55
PTPN6 P29350 1/20 0.55
ALOX5 P09917 1/20 0.53
MEN1 O00255 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
KMT2A Q03164 1/20 0.50
HIF1A Q16665 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15313695 0.88 PTPN1 (0.58) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11209438 0.84 PTPN1 (0.68) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL8772360 0.84 HMGB1 (0.56) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL15313694 0.83 LTA4H (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9804555 0.82 PTPN1 (0.70) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL1456505 0.82 ESR1 (0.56) BCL2BCL2L1ALOX5MEN1KMT2A
SCHEMBL9174306 0.82 PTPN1 (0.70) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL30375403 0.82 ESR1 (0.56) BCL2BCL2L1ALOX5MEN1KMT2A
SCHEMBL1904809 0.81 AMY1A (0.58) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL28707306 0.81 PTPN1 (0.73) BCL2BCL2L1PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9002987-A None JP disclosed
JP-H092987-A MEW POLYPHENOL AND ITS PRODUCTION HONSHU CHEM IND CO LTD 1997-01-07 JP disclosed