Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 8/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959455 | 0.98 | MEN1 (0.42) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL10618891 | 0.93 | GAA (0.41) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL10618879 | 0.93 | GAA (0.41) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL10618886 | 0.93 | GAA (0.41) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL7250728 | 0.85 | GAA (0.44) | CYP4F2CYP4A11GAA | |
| SCHEMBL20457453 | 0.84 | FFAR1 (0.48) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19861329 | 0.84 | FFAR1 (0.48) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19861159 | 0.82 | MEN1 (0.49) | MEN1MAPTKMT2AATML3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27574672 | 0.82 | MEN1 (0.49) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL21961903 | 0.81 | MEN1 (0.46) | MEN1KMT2ASMPD1FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007180-B1 | PROSTAGLANDIN ANALOGUE TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-03-30 | — | — | EP | disclosed |
| US-4294972-A | ANTIULCER AGENTS, CARDIOVASCULAR DISORDERS | BEECHAM GROUP LIMITED (GB) | 1981-10-13 | — | — | US | disclosed |
| EP-0007180-A1 | Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them | BEECHAM GROUP PLC (GB) | 1980-01-23 | — | — | EP | disclosed |
| US-4119726-A | ANTISECRETORY AGENTS, BRONCHODILATORS, ANTICOAGULANTS | BEECHAM GROUP LIMITED (GB) | 1978-10-10 | — | — | US | disclosed |