SCHEMBL959455

SCHEMBL959455

CCCCCC(C)(O)CC(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 1/20 0.38
FDPS P14324 5/20 0.37
GGPS1 O95749 3/20 0.37
NAAA Q02083 1/20 0.37
DGKA P23743 1/20 0.37
CYP1A2 P05177 1/20 0.37
SMPD1 P17405 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11209470 0.98 MEN1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL10618891 0.94 GAA (0.41) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL10618879 0.94 GAA (0.41) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL10618886 0.94 GAA (0.41) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL7250728 0.86 GAA (0.44) GAAMGAMSIMGAM2CYP4F2
SCHEMBL21961903 0.83 MEN1 (0.46) MEN1KMT2AFDPSGGPS1SMPD1
SCHEMBL9311001 0.83 FFAR1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL32663592 0.82 ALOX15 (0.38) KMT2AGAAMGAMSIMGAM2
SCHEMBL28017093 0.82 PTPN2 (0.38) MEN1KMT2AL3MBTL1GAAMGAM
SCHEMBL20457453 0.81 FFAR1 (0.48) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11255089-B2 Colored roofing granules with increased solar heat reflectance, solar heat-reflective shingles and process for producing same CERTAINTEED LLC (US) 2022-02-22 US disclosed
US-20200170925-A1 LIP SCRUB COMPOSITION DEANE JEFFREY ALAN (US) 2020-06-04 US disclosed
US-20190292788-A1 Colored Roofing Granules With Increased Solar Heat Reflectance, Solar Heat-Reflective Shingles And Process For Producing Same CERTAINTEED CORPORATION 2019-09-26 US disclosed
US-10316520-B2 Colored roofing granules with increased solar heat reflectance, solar heat-reflective shingles and process for producing same CERTAINTEED CORPORATION (US) 2019-06-11 US disclosed
US-20160083962-A1 COLORED ROOFING GRANULES WITH INCREASED SOLAR HEAT REFLECTANCE, SOLAR HEAT-REFLECTIVE SHINGLES AND PROCESS FOR PRODUCING SAME CERTAINTEED LLC 2016-03-24 US disclosed
US-9200451-B2 Colored roofing granules with increased solar heat reflectance, solar heat-reflective shingles, and process for producing same CERTAINTEED CORPORATION (US) 2015-12-01 US disclosed
US-20140120316-A1 COLORED ROOFING GRANULES WITH INCREASED SOLAR HEAT REFLECTANCE, SOLAR HEAT-REFLECTIVE SHINGLES, AND PROCESS FOR PRODUCING SAME CERTAINTEED LLC 2014-05-01 US disclosed
US-8586618-B2 Furanone compounds and lactam analogues thereof BIOSIGNAL LIMITED (AU) 2013-11-19 US disclosed
US-8535803-B2 Colored roofing granules with increased solar heat reflectance, solar heat-reflective shingles, and process for producing same CERTAINTEED CORPORATION (US) 2013-09-17 US disclosed
US-8501793-B2 Blood flow promoters for cauda equina tissues ONO PHARMACEUTICAL CO., LTD. (JP) 2013-08-06 US disclosed
US-20130034696-A1 COLORED ROOFING GRANULES WITH INCREASED SOLAR HEAT REFLECTANCE, SOLAR HEAT-REFLECTIVE SHINGLES, AND PROCESS FOR PRODUCING SAME CERTAINTEED LLC 2013-02-07 US disclosed
US-20110015238-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES ONO PHARMACEUTICAL CO., LTD. (JP) 2011-01-20 US disclosed
US-7833995-B2 Blood flow promoters for cauda equina tissues ONO PHARMACEUTICAL CO., LTD. (JP) 2010-11-16 US disclosed
US-20100285306-A1 Colored Roofing Granules With Increased Solar Heat Reflectance, Solar Heat-Reflective Shingles, and Process For Producing Same CERTAINTEED LLC 2010-11-11 US disclosed
US-20100035948-A1 Furanone compounds and lactam analogues thereof UNILEVER PLC (GB) 2010-02-11 US disclosed
WO-2008040097-A1 FURANONE COMPOUNDS AND LACTAM ANALOGUES THEREOF BIOSIGNAL LIMITED (AU) 2008-04-10 WO disclosed
US-20080008832-A1 Colored Roofing Granules With Increased Solar Heat Reflectance, Solar Heat-Reflective Shingles, and Process For Producing Same CERTAINTEED CORPORATION 2008-01-10 US disclosed
US-20070129327-A1 Blood flow promoters for cauda equina tissues ONO PHARMACEUTICAL CO., LTD. (JP) 2007-06-07 US disclosed
EP-1707208-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES ONO PHARMACEUTICAL CO., LTD. (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129327-A1 Blood flow promoters for cauda equina tissues PTGFR, PTGIS, PTGIR MEN1 4761/4885MAPT 3722/4885KMT2A 1776/4885
US-20110015238-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES PTGFR, PTGIS, PTGIR MEN1 4761/4885MAPT 3722/4885KMT2A 1776/4885
US-20100035948-A1 Furanone compounds and lactam analogues thereof FDPS, CYP2C19, MRPL21 MEN1 559/4885MAPT 4714/4885KMT2A 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.