Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618879 | 0.88 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10618891 | 0.88 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10618886 | 0.88 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL959455 | 0.86 | MEN1 (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11209470 | 0.85 | MEN1 (0.45) | GAACYP4F2CYP4A11 | |
| SCHEMBL28791001 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10HMGCRCHRM1 | |
| SCHEMBL4996013 | 0.83 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14727725 | 0.81 | LMNA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9946195 | 0.81 | HSD17B10 (0.39) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL32663592 | 0.80 | ALOX15 (0.38) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605716-B2 | By Reformatsky rearrangement of aldehydes, ketones, or imines in presence of zinc | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIES, GMBH (DE) | 2003-08-12 | — | — | US | disclosed |
| US-20020013501-A1 | Process for the preparation of hydroxy and amino compounds | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013501-A1 | Process for the preparation of hydroxy and amino compounds | BCKDK, KHK, HRH1 | GAA 1787/4885MGAM 717/4885SI 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.