SCHEMBL11209577

SCHEMBL11209577

CC(Oc1ccc(F)cc1)C(=O)Cl

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.62
MAPT P10636 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.46
TP53 P04637 2/20 0.45
CYP1A2 P05177 1/20 0.44
GAA P10253 1/20 0.44
CYP2C9 P11712 1/20 0.44
PKM P14618 1/20 0.44
CYP2C19 P33261 1/20 0.44
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44
TAS1R2 Q8TE23 1/20 0.44
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10852195 0.95 ALDH1A1 (0.57) ALDH1A1MAPTSMN1; SMN2LMNAPOLB
SCHEMBL9819072 0.82 CYP1A2 (0.65) ALDH1A1MAPTSMN1; SMN2LMNAPOLB
SCHEMBL8760234 0.82 KMT2A (0.54) ALDH1A1MAPTLMNACYP1A2GAA
SCHEMBL3128488 0.82 CYP1A2 (0.46) ALDH1A1LMNACYP1A2GAACYP2C9
SCHEMBL8761273 0.82 CYP1A2 (0.57) ALDH1A1SMN1; SMN2LMNAPOLBCYP1A2
SCHEMBL12612110 0.82 KMT2A (0.54) ALDH1A1MAPTLMNACYP1A2GAA
SCHEMBL6617425 0.82 ALDH1A1 (0.64) ALDH1A1MAPTSMN1; SMN2LMNAPOLB
SCHEMBL10607544 0.82 CYP1A2 (0.57) ALDH1A1SMN1; SMN2LMNAPOLBCYP1A2
SCHEMBL9818914 0.82 CYP1A2 (0.65) ALDH1A1MAPTSMN1; SMN2LMNAPOLB
SCHEMBL10739345 0.82 TAS1R3 (0.65) ALDH1A1LMNAPOLBCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046184-B1 ARYLOXYALKYL ISOCYANATES AND METHODS FOR THEIR PREPARATION BASF Aktiengesellschaft (DE) 1983-11-23 EP disclosed
EP-0046184-A1 Aryloxyalkyl isocyanates and methods for their preparation BASF Aktiengesellschaft (DE) 1982-02-24 EP disclosed