Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203228 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBL3MBTL1CTRB1 | |
| SCHEMBL3625848 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAAL3MBTL1TDP1LMNA | |
| SCHEMBL1332360 | 0.80 | ALDH1A1 (0.51) | ALDH1A1GAAL3MBTL1TDP1LMNA | |
| SCHEMBL30447196 | 0.80 | HTT (0.55) | ALDH1A1GAAPOLBL3MBTL1TDP1 | |
| SCHEMBL20773790 | 0.79 | MAPK1 (0.57) | ALDH1A1CTRB1CDC25BMAPK1NPC1 | |
| SCHEMBL7215474 | 0.79 | CASP3 (0.50) | ALDH1A1GAAPOLBL3MBTL1CTRB1 | |
| SCHEMBL11590919 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAL3MBTL1TDP1LMNA | |
| SCHEMBL1184723 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAL3MBTL1TDP1LMNA | |
| SCHEMBL2481122 | 0.79 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBL3MBTL1CTRB1 | |
| SCHEMBL76879 | 0.78 | ALDH1A1 (0.62) | ALDH1A1GAAPOLBL3MBTL1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347355-A | Inhibitors of transpeptidase | ABBOTT LABORATORIES (US) | 1982-08-31 | — | — | US | disclosed |
| WO-1982001875-A1 | INHIBITORS OF TRANSPEPTIDASE | ABBOTT LAB (US) | 1982-06-10 | — | — | WO | disclosed |