SCHEMBL11209753

SCHEMBL11209753

CC(C)NCOCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
CCR5 P51681 1/20 0.44
ALDH1A1 P00352 1/20 0.43
RAB9A P51151 1/20 0.43
CA1 P00915 4/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
SIGMAR1 Q99720 2/20 0.41
TACR1 P25103 2/20 0.41
KMT2A Q03164 1/20 0.41
IDO1 P14902 1/20 0.40
BCHE P06276 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26323927 0.82 AGXT (0.45) ALDH1A1RAB9ACA1CA2CA9
SCHEMBL9965791 0.81 SMN1; SMN2 (0.50) TSHRCCR5ALDH1A1RAB9ASIGMAR1
Hydrochloric Acid SCHEMBL4349318 0.79 SMN1; SMN2 (0.49) TSHRCCR5ALDH1A1RAB9ASIGMAR1
SCHEMBL19752807 0.79 TSHR (0.44) TSHRALDH1A1KMT2A
SCHEMBL9153019 0.78 TSHR (0.46) TSHRALDH1A1KMT2A
SCHEMBL723981 0.77 TSHR (0.61) TSHRALDH1A1CA1CA2CA7
SCHEMBL9782591 0.75 ADRB2 (0.62) CA1CA2CA7CA9
SCHEMBL22639802 0.75 ADRB2 (0.62) CA1CA2CA7CA9
SCHEMBL11067846 0.75 ADRB2 (0.62) CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL20141625 0.75 TSHR (0.58) TSHRALDH1A1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0036426-A4 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. INTERX RESEARCH CORP (US) 1983-03-29 EP disclosed
EP-0036426-A1 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. INTERX RESEARCH CORP (US) 1981-09-30 EP disclosed
WO-1981000849-A1 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES INTERX RESEARCH CORP (US) 1981-04-02 WO disclosed