Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209753 | 0.82 | TSHR (0.54) | CA1CA2CA9RAB9AIDO1 | |
| SCHEMBL9617939 | 0.76 | AGXT (0.64) | AGXTKCNH2CA1CA2CA9 | |
| SCHEMBL3161372 | 0.76 | AGXT (0.64) | AGXTKCNH2CA1CA2CA9 | |
| Potassium SCHEMBL586332 | 0.74 | AGXT (0.61) | AGXTKCNH2CA1CA2CA9 | |
| SCHEMBL586154 | 0.74 | AGXT (0.61) | AGXTKCNH2CA1CA2CA9 | |
| Lithium SCHEMBL585057 | 0.74 | AGXT (0.61) | AGXTKCNH2CA1CA2CA9 | |
| SCHEMBL8263617 | 0.74 | AGXT (0.50) | AGXTKCNH2CA1CA2CA9 | |
| SCHEMBL8851013 | 0.73 | SMN1; SMN2 (0.58) | AGXTNPC1RAB9ASMN1; SMN2IDO1 | |
| SCHEMBL9682048 | 0.72 | RAB9A (0.49) | AGXTKCNH2CA1CA2CA9 | |
| SCHEMBL9861794 | 0.72 | AGXT (0.58) | AGXTKCNH2CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255908-A1 | METHODS OF INTRAVENOUSLY ADMINISTERING SOTALOL HYDROCHLORIDE | AltaThera Pharmaceuticals LLC (US) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255908-A1 | METHODS OF INTRAVENOUSLY ADMINISTERING SOTALOL HYDROCHLORIDE | TNNT2, TNNI3, TNNC1 | AGXT 1316/4885KCNH2 287/4885CA1 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.