Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406974 | 0.86 | PARP10 (0.54) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL5729777 | 0.85 | PARP10 (0.53) | ALDH1A1NPC1RAB9AADRB2ADRB1 | |
| SCHEMBL7776919 | 0.85 | PARP10 (0.57) | ALDH1A1NPC1RAB9AADRB2ADRB1 | |
| SCHEMBL29168895 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL29168893 | 0.83 | KDM4E (0.48) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL1785471 | 0.82 | KMT2A (0.69) | ALDH1A1KMT2AMEN1TDP1MAPT | |
| SCHEMBL23748267 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL1668739 | 0.81 | NPC1 (0.67) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL29784242 | 0.81 | NPC1 (0.67) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL28034678 | 0.81 | PKM (0.55) | ALDH1A1KDM4ENPC1RAB9AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4372835-A | Silane-functionalized ultraviolet screen precursors | GENERAL ELECTRIC CO. (US) | 1983-02-08 | — | — | US | disclosed |
| US-4328346-A | Silane-functionalized ultraviolet screen precursors | GENERAL ELECTRIC COMPANY (US) | 1982-05-04 | — | — | US | disclosed |