Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202399 | 0.87 | CSNK2A2 (0.39) | DHFRCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL11206356 | 0.86 | CYP2D6 (0.33) | DHFRESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6546213 | 0.85 | ESR1 (0.42) | ESR1ACP3ADRA2AADRA2BMAPT | |
| SCHEMBL6546985 | 0.82 | ESR1 (0.39) | ESR1CYP2D6ACP3SLC6A2MAPK1 | |
| SCHEMBL11203841 | 0.82 | P2RX7 (0.38) | CYP2D6SLC6A2MAPK1ADRA2AADRA2B | |
| SCHEMBL11204879 | 0.81 | ESR1 (0.45) | ESR1CYP2D6ACP3SLC6A2SLC6A4 | |
| SCHEMBL11173683 | 0.81 | HTT (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3CYP2D6 | |
| SCHEMBL30932846 | 0.80 | CA1 (0.43) | CSNK2A2CSNK2BCSNK2A1CSNK2A3CYP2D6 | |
| SCHEMBL5599467 | 0.77 | CSNK2A2 (0.49) | DHFRCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL146510 | 0.77 | ESR1 (0.56) | ESR1CYP2D6ACP3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |