Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203841 | 0.89 | P2RX7 (0.38) | CYP2D6MAPK1MEN1KMT2A | |
| SCHEMBL11202399 | 0.87 | CSNK2A2 (0.39) | CYP2D6CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL11209769 | 0.86 | DHFR (0.38) | CYP2D6IDO1TDO2CSNK2A2CSNK2B | |
| SCHEMBL6546213 | 0.85 | ESR1 (0.42) | ESR1MAPTL3MBTL1TAAR1MEN1 | |
| SCHEMBL11203834 | 0.85 | MEN1 (0.33) | CYP2D6BRD4IDO1TDO2HEXA | |
| SCHEMBL6546540 | 0.83 | GABRA1 (0.42) | CYP2D6ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6547626 | 0.82 | ADRA2A (0.42) | CYP2D6ESR1MAPK1ALDH1A1MAPT | |
| SCHEMBL11204879 | 0.81 | ESR1 (0.45) | CYP2D6BRD4ESR1NPC1LMNA | |
| SCHEMBL11205794 | 0.81 | KMT2A (0.43) | MAPTKMT2APPARGPPARACA12 | |
| SCHEMBL5599467 | 0.77 | CSNK2A2 (0.49) | CYP2D6BRD4IDO1HEXAHEXB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |