Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27732454 | 0.91 | MAOA (0.51) | MAOAMAOBCARM1PRMT6CTSS | |
| SCHEMBL19184907 | 0.89 | CTSS (0.60) | MAOAMAOBCARM1PRMT6CTSS | |
| SCHEMBL27712291 | 0.82 | MAOA (0.65) | MAOAMAOBCARM1PRMT6CTSS | |
| SCHEMBL1609623 | 0.82 | MAOA (0.58) | MAOAMAOBCARM1PRMT6CTSS | |
| SCHEMBL10071184 | 0.81 | CARM1 (0.65) | MAOAMAOBCARM1PRMT6CTSS | |
| SCHEMBL16385915 | 0.81 | MAOA (0.59) | MAOAMAOBCARM1PRMT6CTSS | |
| SCHEMBL27718598 | 0.81 | MAOA (0.59) | MAOAMAOBCARM1PRMT6CTSS | |
| Formic Acid SCHEMBL27732452 | 0.81 | SLC18A3 (0.54) | MAOAMAOBCCR3 | |
| SCHEMBL3822693 | 0.81 | CCR3 (0.65) | CARM1PRMT6CCR3 | |
| SCHEMBL15062246 | 0.80 | MAOB (0.46) | MAOAMAOBCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042570-B1 | 20-DEOXYROSARAMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-10-19 | — | — | EP | disclosed |
| EP-0042570-A1 | 20-Deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4279896-A | Novel 20-imino macrolide antibacterial agents | SCHERING CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |