Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 3/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | PIKFYVE | Q9Y2I7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622408 | 0.81 | HTT (0.40) | ASIC3PAK4PAK1PKN1PTGES2 | |
| SCHEMBL12391039 | 0.76 | ASIC3 (0.50) | ASIC3PTGES2MAP3K14KMT2AATM | |
| SCHEMBL1466752 | 0.75 | PAK4 (0.42) | ASIC3PAK4PAK1PKN1MAP3K14 | |
| SCHEMBL7851731 | 0.75 | HTT (0.41) | ASIC3PAK4PAK1PKN1MAP3K14 | |
| SCHEMBL16513217 | 0.75 | CYP1A2 (0.40) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL8620900 | 0.75 | ASIC3 (0.44) | ASIC3PTGES2MAP3K14KMT2AATM | |
| SCHEMBL14949230 | 0.75 | PIKFYVE (0.45) | ASIC3PAK4PAK1PKN1MAP3K14 | |
| SCHEMBL31591011 | 0.75 | RXRB (0.45) | ASIC3MAP3K14LMNAL3MBTL1PIK3CD | |
| SCHEMBL13531864 | 0.73 | MELK (0.42) | KMT2ASLC6A4LMNA | |
| SCHEMBL979323 | 0.73 | GRM5 (0.42) | ASIC3PAK4PAK1PKN1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322432-A | Cyclopropanecarboxylic acid alkynyl esters, processes for producing them, and their use as pesticides | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |