Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216394 | 0.94 | ASIC3 (0.41) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL11551623 | 0.89 | HAO1 (0.49) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL12391039 | 0.89 | ASIC3 (0.50) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL22881118 | 0.82 | HRH3 (0.41) | MAPTHAO1PTGES2KMT2AATM | |
| SCHEMBL12711667 | 0.80 | APP (0.47) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL14268091 | 0.80 | ASIC3 (0.49) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL700507 | 0.78 | HTT (0.46) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL13692776 | 0.78 | ASIC3 (0.44) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL6865029 | 0.78 | KIF11 (0.45) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL3448180 | 0.78 | APP (0.54) | ASIC3L3MBTL1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223172-A | DEHYDROGENATION HALOGENATIVE WITH PALLADIUM-PHOSPHINE COMPLEX CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-09-16 | — | — | US | claimed |
| WO-2024240242-A1 | COMPOUND CONTAINING AMIDE-SUBSTITUTED AROMATIC RING, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 正大天晴药业集团股份有限公司 | 2024-11-28 | — | — | WO | disclosed |
| US-11279878-B2 | Birefringent liquid crystal composition comprising alkylsulfanylaryl isothiocyanato tolane compounds | ESSILOR INTERNATIONAL (FR) | 2022-03-22 | — | — | US | disclosed |
| EP-3394206-B1 | BIREFRINGENT LIQUID CRYSTAL COMPOSITION COMPRISING ALKYLSULFANYLARYL ISOTHIOCYANATO TOLANE COMPOUNDS | ESSILOR INT (FR) | 2021-05-05 | — | — | EP | disclosed |
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5626792-A | DIPHENYLACETYLENE ESTERS, THIOESTERS OR DITHIOESTERS | DISPLAYTECH, INC. (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |