Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PRNP | P04156 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.43 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251999 | 1.00 | RXFP1 (0.59) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL11206865 | 1.00 | RXFP1 (0.59) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL11210208 | 1.00 | RXFP1 (0.59) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL11205241 | 1.00 | RXFP1 (0.59) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL11210650 | 0.98 | RXFP1 (0.56) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL11251729 | 0.93 | RXFP1 (0.50) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL9794742 | 0.86 | RPS6KB2 (0.43) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL12664443 | 0.84 | ALDH1A1 (0.41) | ALDH1A1POLBMAPT | |
| SCHEMBL20391283 | 0.84 | ALDH1A1 (0.41) | RXFP1LMNAALDH1A1PRNPRECQL | |
| SCHEMBL11235323 | 0.82 | HPGD (0.64) | RXFP1LMNAALDH1A1PRNPRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029247-B1 | ALKENYL THIENYL ALKANE CARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1983-04-13 | — | — | EP | disclosed |
| US-4309407-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTI-ARTERIOSCLEROTIC | A. NATTERMANN & CIE. GMBH (DE) | 1982-01-05 | — | — | US | disclosed |
| EP-0029247-A1 | Alkenyl thienyl alkane carboxylic acids and their derivatives, process for their preparation and medicaments containing them | A. Nattermann & Cie. GmbH (DE) | 1981-05-27 | — | — | EP | disclosed |