Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209038 | 1.00 | HPGD (0.64) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL11247358 | 1.00 | HPGD (0.64) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL11210790 | 1.00 | HPGD (0.64) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL11204556 | 1.00 | HPGD (0.64) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL2224980 | 0.94 | HPGD (0.56) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL28388339 | 0.88 | RPS6KB2 (0.49) | HPGDALDH1A1LMNAPOLBRPS6KB2 | |
| SCHEMBL11251999 | 0.82 | RXFP1 (0.59) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL11205241 | 0.82 | RXFP1 (0.59) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL11209866 | 0.82 | RXFP1 (0.59) | HPGDALDH1A1LMNAPRNPRECQL | |
| SCHEMBL11206865 | 0.82 | RXFP1 (0.59) | HPGDALDH1A1LMNAPRNPRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309407-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTI-ARTERIOSCLEROTIC | A. NATTERMANN & CIE. GMBH (DE) | 1982-01-05 | — | — | US | disclosed |