Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CBS | P35520 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209239 | 1.00 | MAPT (0.54) | MAPTRXFP1ALOX5ACHESGMS1 | |
| SCHEMBL11204332 | 1.00 | MAPT (0.54) | MAPTRXFP1ALOX5ACHESGMS1 | |
| SCHEMBL11204989 | 1.00 | MAPT (0.54) | MAPTRXFP1ALOX5ACHESGMS1 | |
| SCHEMBL11203911 | 0.98 | ALOX5 (0.53) | MAPTRXFP1ALOX5ACHESGMS1 | |
| SCHEMBL11133561 | 0.94 | ALOX5 (0.53) | MAPTALOX5HDAC1HDAC2ALDH1A1 | |
| SCHEMBL7299043 | 0.88 | MAPT (0.53) | MAPTALOX5HDAC1HDAC2ALDH1A1 | |
| SCHEMBL11206627 | 0.86 | HDAC3 (0.49) | MAPTHDAC1HDAC2FAAHALDH1A1 | |
| SCHEMBL10384113 | 0.86 | HDAC3 (0.49) | MAPTHDAC1HDAC2FAAHALDH1A1 | |
| SCHEMBL10875510 | 0.85 | SMN1; SMN2 (0.51) | MAPTALOX5HDAC1HDAC2ALDH1A1 | |
| SCHEMBL7640337 | 0.85 | MAPT (0.57) | MAPTRXFP1ALOX5HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |