SCHEMBL7299043

SCHEMBL7299043

C=C(CCc1ccccc1)C(=O)OCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KEAP1 Q14145 1/20 0.48
ABCB1 P08183 1/20 0.48
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
FFAR1 O14842 1/20 0.46
ALOX5 P09917 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11133561 0.90 ALOX5 (0.53) MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2
SCHEMBL11203911 0.89 ALOX5 (0.53) MAPTALDH1A1L3MBTL1SMN1; SMN2ALOX5
SCHEMBL11210249 0.88 MAPT (0.54) MAPTALDH1A1SMN1; SMN2ALOX5HDAC1
SCHEMBL11204332 0.88 MAPT (0.54) MAPTALDH1A1SMN1; SMN2ALOX5HDAC1
SCHEMBL11209239 0.88 MAPT (0.54) MAPTALDH1A1SMN1; SMN2ALOX5HDAC1
SCHEMBL11204989 0.88 MAPT (0.54) MAPTALDH1A1SMN1; SMN2ALOX5HDAC1
SCHEMBL12812895 0.85 CYP4F2 (0.57) MAPTALDH1A1TDP1SMN1; SMN2KMT2A
SCHEMBL7398418 0.85 TDP1 (0.53) MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2
SCHEMBL11291139 0.84 LMNA (0.47) MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2
SCHEMBL14397264 0.83 TDP1 (0.51) MAPTALDH1A1TDP1SMN1; SMN2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637531-B2 Pigment dispersant composition, production method therefor, pigment dispersion, and actinic-ray-curable ink-jet ink DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2026-05-26 US disclosed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
EP-4209559-B1 PIGMENT DISPERSANT COMPOSITION, PRODUCTION METHOD THEREFOR, PIGMENT DISPERSION, AND ACTINIC-RAY-CURABLE INK-JET INK DAINICHISEIKA COLOR CHEM (JP) 2025-01-29 EP disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
US-20230357479-A1 PIGMENT DISPERSANT COMPOSITION, PRODUCTION METHOD THEREFOR, PIGMENT DISPERSION, AND ACTINIC-RAY-CURABLE INK-JET INK DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-11-09 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-116568310-A Boric acid compounds 株式会社LG化学 2023-08-08 CN disclosed
EP-4209559-A1 PIGMENT DISPERSANT COMPOSITION, PRODUCTION METHOD THEREFOR, PIGMENT DISPERSION, AND ACTINIC-RAY-CURABLE INK-JET INK DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-07-12 EP disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed
US-5591891-A PEPTIDASE INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1997-01-07 US disclosed
EP-0733642-A1 Benzazepin-, benzoxazepin- and benzothiazepin-N-acetic acid-derivatives, their preparation and their pharmaceutical compositions Kali-Chemie Pharma GmbH (DE) 1996-09-25 EP disclosed
US-5192800-A Hypotensive agents PFIZER INC. (US) 1993-03-09 US disclosed
EP-0274234-B1 SPIRO-SUBSITUTED GLUTARAMIDE DIURETIC AGENTS Pfizer Limited (GB) 1991-09-11 EP disclosed
US-5030654-A Glutaramide diuretic agents PFIZER INC. (US) 1991-07-09 US disclosed
EP-0274234-A2 Spiro-subsituted glutaramide diuretic agents Pfizer Limited (GB) 1988-07-13 EP disclosed
US-4665087-A ANGIOTENSIN-CONVERTING ENZYME INHIBITORS CIBA-GEIGY CORPORATION (US) 1987-05-12 US disclosed
US-4624962-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-25 US disclosed
US-4515803-A HYPOTENSIVES Hoechst Aktiengesellschafat (DE) 1985-05-07 US disclosed
US-4324796-A HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 MAPT 3120/4885ALDH1A1 3621/4885L3MBTL1 393/4885
US-12637531-B2 Pigment dispersant composition, production method therefor, pigment dispersion, and actinic-ray-curable ink-jet ink VCL, DYNLL1, DYNLL2 MAPT 649/4885ALDH1A1 253/4885L3MBTL1 279/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 MAPT 685/4885ALDH1A1 2005/4885L3MBTL1 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.