Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.50 |
| ▸ | ATG7 | O95352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 4/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213318 | 1.00 | ADA (0.50) | ADAATG7TP53SMN1; SMN2ADK | |
| SCHEMBL9350433 | 0.89 | ATG7 (0.53) | ADAATG7SMN1; SMN2ADKSLC29A1 | |
| SCHEMBL11210952 | 0.89 | SLC29A1 (0.49) | ADAATG7SLC29A1 | |
| SCHEMBL30935868 | 0.88 | ADA (0.47) | ADAATG7ADKSLC29A1HSPA5 | |
| SCHEMBL30935809 | 0.87 | SLC29A1 (0.50) | ADAATG7SLC29A1 | |
| SCHEMBL29273711 | 0.87 | SLC29A1 (0.50) | ADAATG7SLC29A1 | |
| SCHEMBL29273715 | 0.85 | SLC29A1 (0.52) | ADAADKSLC29A1 | |
| SCHEMBL30935808 | 0.85 | SLC29A1 (0.52) | ADAADKSLC29A1 | |
| SCHEMBL11210320 | 0.84 | SLC29A1 (0.48) | ADASLC29A1 | |
| SCHEMBL29273714 | 0.84 | SLC29A1 (0.64) | ATG7ADKSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355022-A | Nucleoside analogues for the treatment of parasitic infections | 安特卫普大学 | 2024-07-16 | — | — | CN | disclosed |
| EP-0021293-B1 | 4-SUBSTITUTED THIO-1-BETA-D-RIBOFURANOSYLPYRAZOLO(3,4-D) PYRIMIDINES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS AND MEDICAL USES | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-09-07 | — | — | EP | disclosed |
| US-4299823-A | TREATMENT OF COCCIDIOSIS | BURROUGHS WELLCOME CO. (US) | 1981-11-10 | — | — | US | disclosed |
| US-4299824-A | TREATMENT OF COCCIDIOSIS | BURROUGHS WELLCOME CO. (US) | 1981-11-10 | — | — | US | disclosed |
| EP-0021293-A2 | 4-Substituted thio-1-beta-D-ribofuranosylpyrazolo(3,4-D) pyrimidines, processes for their preparation, pharmaceutical formulations and medical uses | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |