Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 1/20 | 0.53 |
| ▸ | ADA | P00813 | 1/20 | 0.51 |
| ▸ | ADK | P55263 | 3/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.50 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | ROS1 | P08922 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210339 | 0.89 | ADA (0.50) | ATG7ADAADKDOT1LDCLK1 | |
| SCHEMBL11213318 | 0.89 | ADA (0.50) | ATG7ADAADKDOT1LDCLK1 | |
| SCHEMBL11210952 | 0.87 | SLC29A1 (0.49) | ATG7ADASLC29A1 | |
| SCHEMBL30935868 | 0.86 | ADA (0.47) | ATG7ADAADKDOT1LHSPA5 | |
| SCHEMBL30935809 | 0.85 | SLC29A1 (0.50) | ATG7ADASLC29A1 | |
| SCHEMBL29273711 | 0.85 | SLC29A1 (0.50) | ATG7ADASLC29A1 | |
| SCHEMBL1737936 | 0.85 | ATG7 (0.69) | ATG7ADAADKDOT1LDCLK1 | |
| SCHEMBL29325546 | 0.85 | ATG7 (0.69) | ATG7ADAADKDOT1LDCLK1 | |
| SCHEMBL4085704 | 0.85 | ATG7 (0.69) | ATG7ADAADKDOT1LDCLK1 | |
| SCHEMBL29325550 | 0.85 | ATG7 (0.69) | ATG7ADAADKDOT1LDCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0353268-A4 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RES INST (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0353268-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RESEARCH INST (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989005817-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-06-29 | — | — | WO | disclosed |