Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28744776 | 0.96 | TDP1 (0.40) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| Glycerin SCHEMBL11218601 | 0.87 | LMNA (0.39) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL28778827 | 0.82 | TSHR (0.35) | TSHRALDH1A1 | |
| Alcohol SCHEMBL381890 | 0.81 | — | — | |
| Ethylene Glycol SCHEMBL1423158 | 0.81 | ALDH1A1 (0.36) | TDP1LMNATSHRALDH1A1 | |
| SCHEMBL1438 | 0.81 | — | — | |
| SCHEMBL7529535 | 0.81 | ALDH1A1 (0.44) | TDP1LMNATSHRALDH1A1 | |
| Lactic Acid SCHEMBL547542 | 0.80 | TP53 (0.50) | TSHRALDH1A1 | |
| Alcohol SCHEMBL1684991 | 0.79 | ALDH1A1 (0.36) | TDP1LMNATSHRALDH1A1HPGD | |
| Allyl Alcohol SCHEMBL14631934 | 0.79 | TSHR (0.45) | TDP1USP2CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115851184-B | Environment-friendly transfer adhesive and preparation method and application thereof | 广东天龙油墨有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-115851184-A | Environment-friendly transfer glue and preparation method and application thereof | 广东天龙油墨有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115851184-B | Environment-friendly transfer adhesive and preparation method and application thereof | 广东天龙油墨有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-117661376-A | Physical antibacterial tipping paper for cigarettes and preparation method thereof | 深圳劲嘉集团股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-115851184-A | Environment-friendly transfer glue and preparation method and application thereof | 广东天龙油墨有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-106318241-B | Adhesive film and display member including the same | 三星SDI株式会社 | 2020-03-24 | — | — | CN | disclosed |
| CN-104448313-A | Weakly basic polymer resin, preparation method, retarding layer comprising weakly basic polymer resin as well as solar cell | SUZHOU FIRST PV MATERIAL CO LTD | 2015-03-25 | — | — | CN | disclosed |
| EP-0044832-A4 | PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES. | BLOUNT DAVID H | 1982-07-06 | — | — | EP | disclosed |
| EP-0044832-A1 | PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES | BLOUNT, David H. (US) | 1982-02-03 | — | — | EP | disclosed |
| WO-1981002300-A1 | PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES | BLOUNT D | 1981-08-20 | — | — | WO | disclosed |