Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356140 | 0.77 | CYP3A4 (0.50) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL29369823 | 0.77 | CYP3A4 (0.50) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL11210380 | 0.73 | CYP3A4 (0.37) | CYP3A4TDP1 | |
| SCHEMBL28377763 | 0.72 | CYP3A4 (0.45) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL673041 | 0.71 | KMT2A (0.44) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL3991493 | 0.69 | CYP3A4 (0.42) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL10801387 | 0.69 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL1415413 | 0.68 | ALDH1A1 (0.46) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL7128955 | 0.68 | CYP3A4 (0.46) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL11603236 | 0.68 | HPGD (0.45) | CYP3A4ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022750-B1 | 1,3,4-THIADIAZOLYLOXY-PHENYL UREAS, THEIR PREPARATION AND HERBICIDES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | claimed |
| EP-0022750-A1 | 1,3,4-Thiadiazolyloxy-phenyl ureas, their preparation and herbicides containing them | CIBA-GEIGY AG (CH) | 1981-01-21 | — | — | EP | claimed |
| EP-0022750-B1 | 1,3,4-THIADIAZOLYLOXY-PHENYL UREAS, THEIR PREPARATION AND HERBICIDES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| US-4364769-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| EP-0022750-A1 | 1,3,4-Thiadiazolyloxy-phenyl ureas, their preparation and herbicides containing them | CIBA-GEIGY AG (CH) | 1981-01-21 | — | — | EP | disclosed |