Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50333 | 0.75 | CYP3A4 (0.54) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL4544188 | 0.75 | CYP3A4 (0.54) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL4551613 | 0.75 | CYP3A4 (0.54) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11210370 | 0.73 | CYP3A4 (0.35) | CYP3A4TDP1 | |
| SCHEMBL6264790 | 0.72 | LTA4H (0.44) | TSHR | |
| SCHEMBL10558423 | 0.70 | SMN1; SMN2 (0.56) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL1415412 | 0.70 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL8156347 | 0.69 | FBP1 (0.42) | TSHR | |
| SCHEMBL242048 | 0.69 | LTA4H (0.50) | CYP3A4TSHR | |
| SCHEMBL14493735 | 0.69 | CYP3A4 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022750-B1 | 1,3,4-THIADIAZOLYLOXY-PHENYL UREAS, THEIR PREPARATION AND HERBICIDES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | claimed |
| EP-0022750-A1 | 1,3,4-Thiadiazolyloxy-phenyl ureas, their preparation and herbicides containing them | CIBA-GEIGY AG (CH) | 1981-01-21 | — | — | EP | claimed |
| EP-0022750-B1 | 1,3,4-THIADIAZOLYLOXY-PHENYL UREAS, THEIR PREPARATION AND HERBICIDES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| US-4364769-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| EP-0022750-A1 | 1,3,4-Thiadiazolyloxy-phenyl ureas, their preparation and herbicides containing them | CIBA-GEIGY AG (CH) | 1981-01-21 | — | — | EP | disclosed |