Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219671 | 0.83 | LMNA (0.50) | LMNACYP2C19HSD17B10 | |
| SCHEMBL11210570 | 0.83 | LMNA (0.50) | LMNACYP2C19HSD17B10 | |
| SCHEMBL11213089 | 0.81 | ACE (0.43) | — | |
| SCHEMBL11212426 | 0.80 | ACE (0.31) | — | |
| SCHEMBL11208686 | 0.78 | LMNA (0.34) | LMNACYP2C19HSD17B10 | |
| SCHEMBL11210192 | 0.77 | ACE (0.38) | — | |
| SCHEMBL11257080 | 0.76 | ACE (0.37) | — | |
| SCHEMBL11213000 | 0.76 | ACE (0.50) | — | |
| SCHEMBL11210160 | 0.76 | ACE (0.37) | — | |
| SCHEMBL11211954 | 0.75 | ACE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311697-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-19 | — | — | US | disclosed |