SCHEMBL11210401

SCHEMBL11210401

[O-][n+]1cccc2cc(Nc3ccccc3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
HSD17B10 Q99714 4/20 0.55
CYP3A4 P08684 3/20 0.55
HPGD P15428 3/20 0.55
SNCA P37840 1/20 0.44
MAPT P10636 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
AR P10275 1/20 0.44
L3MBTL1 Q9Y468 5/20 0.43
ALOX12 P18054 4/20 0.43
TSHR P16473 3/20 0.43
MAPK1 P28482 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
ALOX15 P16050 2/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
PTGS2 P35354 1/20 0.43
HTR2B P41595 1/20 0.43
TERT O14746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12275774 0.74 ATM (0.41) ALDH1A1MAPTLMNAATMSMN1; SMN2
SCHEMBL1778288 0.72 HTR6 (0.45) ALDH1A1MAPTL3MBTL1TSHRHTR2B
Diphenylamine SCHEMBL28300967 0.72 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4HPGDSNCA
SCHEMBL11466814 0.72 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4HPGDSNCA
SCHEMBL38433 0.72 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4HPGDSNCA
Benzene SCHEMBL28342167 0.72 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4HPGDSNCA
SCHEMBL29354421 0.72 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4HPGDSNCA
SCHEMBL9531 0.71 ATM (0.48) ATM
SCHEMBL11961726 0.71 ALDH1A1 (0.91) ALDH1A1HSD17B10CYP3A4HPGDSNCA
SCHEMBL2794436 0.70 ALDH1A1 (0.87) ALDH1A1HSD17B10CYP3A4HPGDSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012432-B1 LIGHT-STABLE QUINACRIDONEQUINONE YELLOW PIGMENT AND POST TREATMENT TO IMPROVE ITS DISPERSIBILITY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-26 EP claimed
US-4286998-A CONTAINING 2-ANILINOACRIDONE, 5,6,7,8-TETRAHYDRO-2-ANALINOACRIDONE, 6-ANILINOQUINOLONE OR 2-AMINOACRIDONE AS A STABILIZER E. I. DUPONT DE NEMOURS AND COMPANY (US) 1981-09-01 US claimed
EP-0012432-A1 Light-stable quinacridonequinone yellow pigment and post treatment to improve its dispersibility E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-06-25 EP claimed
EP-0012432-B1 LIGHT-STABLE QUINACRIDONEQUINONE YELLOW PIGMENT AND POST TREATMENT TO IMPROVE ITS DISPERSIBILITY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-26 EP disclosed
US-4286998-A CONTAINING 2-ANILINOACRIDONE, 5,6,7,8-TETRAHYDRO-2-ANALINOACRIDONE, 6-ANILINOQUINOLONE OR 2-AMINOACRIDONE AS A STABILIZER E. I. DUPONT DE NEMOURS AND COMPANY (US) 1981-09-01 US disclosed
US-4286998-A CONTAINING 2-ANILINOACRIDONE, 5,6,7,8-TETRAHYDRO-2-ANALINOACRIDONE, 6-ANILINOQUINOLONE OR 2-AMINOACRIDONE AS A STABILIZER E. I. DUPONT DE NEMOURS AND COMPANY (US) 1981-09-01 US disclosed
EP-0012432-A1 Light-stable quinacridonequinone yellow pigment and post treatment to improve its dispersibility E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-06-25 EP disclosed
EP-0012432-A1 Light-stable quinacridonequinone yellow pigment and post treatment to improve its dispersibility E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-06-25 EP disclosed