Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444446 | 0.68 | KDM4E (0.42) | KDM4ECYP3A4ALOX15ABCC9ABCB1 | |
| SCHEMBL11216758 | 0.66 | ABCB1 (0.39) | KDM4EABCC9ABCB1ABCC8KCNJ11 | |
| SCHEMBL11219476 | 0.65 | ABCB1 (0.39) | KDM4EABCC9ABCB1 | |
| SCHEMBL11461363 | 0.64 | KDM4E (0.37) | KDM4ECYP3A4ALOX15ABCC9ABCB1 | |
| SCHEMBL11453213 | 0.64 | KDM4E (0.39) | KDM4ECYP3A4ALOX15ABCC9ABCB1 | |
| SCHEMBL11210696 | 0.63 | ABCB1 (0.38) | KDM4ECYP3A4ALOX15ABCC9ABCB1 | |
| SCHEMBL10908689 | 0.63 | KDM4E (0.77) | KDM4ECYP3A4ALOX15ABCC9ABCB1 | |
| SCHEMBL11210701 | 0.63 | ABCB1 (0.36) | ABCC9ABCB1 | |
| SCHEMBL7067974 | 0.63 | TSHR (0.53) | KDM4EAR | |
| SCHEMBL11221894 | 0.63 | ABCC9 (0.41) | KDM4EABCC9ABCB1ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |