Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL11210759 | 0.82 | KDM4E (0.35) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11211408 | 0.82 | KDM4E (0.35) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11568956 | 0.80 | TSHR (0.50) | TDP1TSHRNAPRT | |
| Pyridine SCHEMBL11569632 | 0.79 | KDM4E (0.36) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11208438 | 0.79 | KDM4E (0.36) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11210325 | 0.79 | KDM4E (0.33) | KDM4EGAATDP1CYP3A4 | |
| Pyridine SCHEMBL11569993 | 0.78 | KDM4E (0.33) | KDM4EGAA | |
| SCHEMBL27538676 | 0.78 | TDP1 (0.50) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11204043 | 0.77 | KDM4E (0.34) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11205969 | 0.75 | KDM4E (0.33) | KDM4EGAATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0003897-A1 | Phosphinegold(I)salts, process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-09-05 | — | — | EP | disclosed |