Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL11210901 | 0.87 | LMNA (0.32) | TDP1CYP3A4 | |
| Pyridine SCHEMBL11207622 | 0.87 | SMN1; SMN2 (0.35) | KDM4EGAACYP3A4 | |
| Pyridine SCHEMBL11204043 | 0.86 | KDM4E (0.34) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11569873 | 0.84 | CYP17A1 (0.39) | KDM4ETDP1CYP3A4 | |
| Pyridine SCHEMBL11211408 | 0.84 | KDM4E (0.35) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11206542 | 0.83 | ALDH1A1 (0.35) | KDM4EGAATDP1TSHR | |
| Pyridine SCHEMBL11210777 | 0.83 | KMT2A (0.43) | KDM4ETDP1CYP3A4 | |
| Pyridine SCHEMBL11210161 | 0.81 | GAA (0.33) | KDM4EGAATDP1CYP3A4NOTUM | |
| Pyridine SCHEMBL11210907 | 0.79 | KDM4E (0.39) | KDM4EGAATDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11204444 | 0.79 | KDM4E (0.32) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-A1 | Phosphinegold(I)salts, process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-09-05 | — | — | EP | disclosed |