Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL11569414 | 0.89 | CYP3A4 (0.42) | KDM4EGAATDP1CYP3A4PTGS2 | |
| Pyridine SCHEMBL11205969 | 0.81 | KDM4E (0.33) | KDM4EGAATDP1CYP3A4 | |
| Pyridine SCHEMBL11210907 | 0.79 | KDM4E (0.39) | KDM4EGAATDP1CYP3A4TSHR | |
| SCHEMBL196040 | 0.78 | CYP3A4 (0.45) | KDM4ETDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11212974 | 0.77 | CYP2D6 (0.36) | KDM4ETDP1CYP3A4TSHR | |
| SCHEMBL30679662 | 0.76 | CYP3A4 (0.43) | KDM4ETDP1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL28639460 | 0.76 | CYP3A4 (0.43) | KDM4ETDP1CYP3A4TSHR | |
| Pyridine SCHEMBL11213166 | 0.76 | KDM4E (0.32) | KDM4EGAA | |
| Pyridine SCHEMBL11569632 | 0.75 | KDM4E (0.36) | KDM4EGAATDP1CYP3A4TSHR | |
| SCHEMBL28403849 | 0.74 | CYP3A4 (0.38) | KDM4EGAATDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4171360-A | Phosphinegold (I) salts having antiarthritic activity | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |